Conformational analysis and vibrational spectroscopic investigation of L-alanyl-L-glutamine dipeptide
نویسندگان
چکیده
منابع مشابه
Intestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,15N]glutamine or L-[2,15N]glutamine in mice.
Previously, we observed increased plasma arginine (ARG) concentrations after glutamine (GLN)-enriched diets, in combination with clinical benefits. GLN delivers nitrogen for ARG synthesis, and the present study was designed to quantify the interorgan relationship of exogenous L-GLN or GLN dipeptide, by enteral or parenteral route, contributing to intestinal citrulline (CIT) and renal de novo AR...
متن کاملEnhancement of endotoxic shock by N-acetylmuramyl-L-alanyl-(L-seryl)-D-isoglutamine (muramyl dipeptide).
We described elsewhere that the synergistic antitumor activity of endotoxic extracts from Re mutants of gram-negative bacteria and trehalose mycolate against guinea pig syngeneic line 10 tumor was abrogated after peptide substances accompanying these extracts had been removed. This activity could be restored by combining peptide-free endotoxin either with cell wall skeleton from Bacillus Calmet...
متن کاملIntestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,N]glutamine or L-[2,N]glutamine in mice
Boelens, Petra G., Paul A. M. van Leeuwen, Cornelis H. C. Dejong, and Nicolaas E. P. Deutz. Intestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,N]glutamine or L-[2,N]glutamine in mice. Am J Physiol Gastrointest Liver Physiol 289: G679–G685, 2005. First published July 28, 2005; doi:10.1152/ajpgi.00026.2005.—Previously, we observed ...
متن کاملNeural-network analysis of the vibrational spectra of N-acetyl L-alanyl N'-methyl amide conformational states.
Density-functional theory (DFT) calculations utilizing the Becke 3LYP hybrid functional have been carried out for N-acetyl L-alanine N'-methylamide and examined with respect to the effect of water on the structure, the vibrational frequencies, vibrational absorption (VA), vibrational circular dichroism (VCD), Raman spectra, and Raman optical activity (ROA) intensities. The large changes due to ...
متن کاملL-Alanyl-Glutamine Attenuates Oxidative Stress in Liver Transplantation Patients.
BACKGROUND Ischemia/reperfusion injury during liver transplantation can cause severe damage to the graft. The objective of this randomized, double-blind study was to evaluate the possible protective effects of L-alanyl-glutamine on the liver graft. METHODS The sample included 33 patients from a liver transplantation service in Northeastern Brazil. Before cold ischemia, the patients received 5...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Spectroscopy
سال: 2010
ISSN: 0712-4813,1875-922X
DOI: 10.1155/2010/917414